Accomplishments
Coherence Tomorgraphy: Technological Research and Development
- A non-contact, wide-field optoacoustic tomography method using time-resolved interferometric imaging of surface displacement was demonstrated with ~50-100 μm resolution in cm-thick turbid tissue phantoms. (S. Carp et al., 2004, 2005)
- A photonic crystal fiber was used for broadband continuum generation and integrated into an ultrahigh resolution OCT system. (Y. Wang et al., 2003)
- Optical coherence tomography using second harmonic generation contrast was demonstrated in both conventional and high-resolution modes. (Y. Jiang et al., 2004, 2005)
- A rotational MEMS probe was integrated into an OCT endoscope platform and used to acquire intralumenal images in vivo. (P. Tran et al., 2004)
- A fiber-based polarization-sensitive OCT probe was developed and used to acquire depth-resolved birefringence images. (S. Guo et al., 2004)
- Electro-optical phase modulation techniques were introduced to enhance S/N and remove mirror image artifacts in frequency-domain OCT. (J. Zhang et al., 2005)
Fourier domain OCT with 1 µm center wavelength swept source to image retina and choroidal morphology and blood flow.
- A 1 micron fiber laser source was used to generate ultra-high resolution OCT images. (H. Lim et al., 2005)
- A two-axis MEMS scanning mirror was integrated into an OCT endoscope and used to demonstrate 3-dimensional subsurface tomographic imaging. (W. Jung et al., 2006)
- Fast Fourier-domain OCT was demonstrated using a 1 micron swept laser source (W. Jung et al, 2006), and swept-source Fourier-domain optical Doppler tomography of blood flow was demonstrated in an in vivo animal model. (J. Zhang and Z. Chen, 2005)
- A fiber bundle-based OCT system was developed for clinical endoscopic imaging. (T. Xie et al., 2005)
