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Interferometric switching of coherent anti-Stokes Raman scattering signals in microscopy

Abstract
Coherent anti-Stokes Raman scattering _CARS_ interferometry is used to deplete the anti-Stokes radiation emerging from a tightly focused spot. Near-to-complete depletion of the anti-Stokes radiation is obtained when a phase-controlled local oscillator field at the anti-Stokes frequency is out of phase with the induced CARS field in the focal volume. Unlike in traditional interferometry, this depleted energy is not spatially redistributed. A theoretical analysis shows that the energy loss in the anti-Stokes channel is accompanied by an energy gain in the pump and Stokes channels. Interferometric switching of anti-Stokes radiation may offer a route toward developing high-resolution CARS microscopy.

Interferometric switching of coherent anti-Stokes Raman scattering signals in microscopy Alexei Nikolaenko, Vishnu Vardhan Krishnamachari, and Eric Olaf Potma* Department of Chemistry, Natural Sciences II, University of California, Irvine, California 92697, USA Physical Review A, Vol, 79, 013823 (2009) NIHMS 165169

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