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The Swedish CArdioPulmonary BioImage Study

Dr Sara Bergstrand and Dr Hanna Jonasson,

The Swedish CArdioPulmonarybioImage Study (SCAPIS) combines the use of new imaging technologies, advances in large-scale omics, Swedish registers and epidemiological analyses and wellness profiling. It will be a nationwide, open-access, population-based cohort for the study of CVD and chronic obstructive pulmonary disease. The cohort includes 30 000 men and women aged between 50 and 64 years and the information obtained will be used to improve risk prediction of cardiopulmonary diseases and optimize the ability to study disease mechanisms.
As part of the local study program at Linköping University, a study of the skin microcirculation is performed including 5 000 individuals. The relationship between microvascular function and cardiovascular diseases and diabetes is studied using an instrument with combined Laser Doppler Flowmetry (LDF) and Diffuse reflectance spectroscopy (DRS) with a data analysis based on an adaptive individualized skin tissue light transport model. A long term goal is to establish microcirculatory dysfunction as a predictor for cardiovascular diseases.
The seminar will present the method and the first results from the ongoing measurements and also allow for a discussion of adding other optical measurement methods.

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