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LASER MICROBEAM AND MEDICAL PROGRAM (LAMMP) SEMINARS

Latest time-resolving CMOS image sensors and applications for 3D profile, fluorescence lifetime, and tissue imaging

Prof. Min-Woong Seo, Prof. Keita Yasutomi, and Prof. Shoji Kawahito

The latest achievements of time-resolving CMOS image sensors with a pico-second-regime time resolution at Shizuoka University are presented. Their applications cover high-resolution 3D profile imaging, fluorescence lifetime imaging based on induced fluorescent dyes or endogenous fluorescent coenzymes, and tissue absorption and scattering imaging with short pulse lasers. Time-of-Flight-based 3D range imager with 132x120 pixels and 0.25mm range resolution, which corresponds to 1.7-ps time resolution, is demonstrated. The developed FLIM CMOS imager achieves extremely high time resolution of 10ps, very quick intrinsic response of 180ps at 374nm, and very low temporal noise of 1.7-e-rms with true correlated double sampling operation.

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